Cah and vaginal development

Anatomical and functional outcomes of feminizing genitoplasty for ambiguous genitalia in patients with virilizing congenital adrenal hyperplasia. The ideal surgical technique and appropriate age for performing feminizing genitoplasty are debatable, and few long-term outcome studies have been reported. PURPOSE: To report a retrospective study on anatomical and functional outcomes of feminizing genitoplasty in patients with virilizing congenital adrenal hyperplasia. Follow-up ranged from 2 to 16 years. Clitoral length ranged from 1. The surgical technique included clitorovaginoplasty in a single procedure and was carried out before 2 years of age in 18 patients.
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Feminizing genital reconstruction in congenital adrenal hyperplasia

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Congenital Adrenal Hyperplasia

The past several decades have seen multiple advances in the surgical reconstruction for girls born with Disorders of Sexual Differentiation. This surgery can be technically very demanding, and must be individualized for each patient, as the degree of virilization and level of confluence of the vagina and urogenital sinus will dictate the surgical approach. In this manuscript we present our approach and experience in the surgical options for girls born with Congenital Adrenal Hyperplasia, with special attention regarding clitoroplasty, urogenital mobilization, and vaginoplasty. Few areas in pediatric urology are more challenging and controversial than genital reconstruction for girls with virilization. This situation is most commonly seen as a result of congenital adrenal hyperplasia CAH. Debate exists mainly regarding the optimal timing and extent of genital reconstruction for these children. Additionally, the surgical reconstruction itself can be difficult, requiring meticulous attention to detail and tissue handling.
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Gastaud, C. Bouvattier, L. Duranteau, R. Brauner, E. Thibaud, F.
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Congenital adrenal hyperplasia CAH most commonly due to hydroxylase deficiency is the most common type of disorder of sex development. This review will focus on CAH addressing historical and current surgical techniques with their anatomical foundations, with special attention to long-term results and outcomes on sexual function, patient satisfaction, patient attitude toward surgery, and ongoing controversies in management of these patients. The last century has witnessed from the description of the DNA, the basis of genetic information, to the entire sequencing of the human genome 1. Huge advances in all areas of science and technology have revolutionized humanity and the way we live, think, and work.
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