Bacterial vaginosis BV is a common vaginal bacterial imbalance associated with risk for HIV and poor gynecologic and obstetric outcomes. Male circumcision reduces BV-associated bacteria on the penis and decreases BV in female partners, but the link between penile microbiota and female partner BV is not well understood. We tested the hypothesis that having a female partner with BV increases BV-associated bacteria in uncircumcised men. We characterized penile microbiota composition and density i. Men with two or more extramarital partners were significantly more likely to have CST4 to 7 than men with only marital partners CST4 to 7 prevalence ratio, 1.
Penile Microbiota and Female Partner Bacterial Vaginosis in Rakai, Uganda
Bacterial vaginosis: are men involved? | Biocodex Microbiote Institute
Metrics details. Bacterial vaginosis BV is estimated to affect 1 in 3 women globally and is associated with obstetric and gynaecological sequelae. Evidence of male carriage of BV-organisms suggests that male partners may be reinfecting women with BV-associated bacteria henceforth referred to as BV-organisms and impacting on the efficacy of treatment approaches solely directed to women. This trial aims to determine the effect of concurrent male partner treatment for preventing BV recurrence compared to current standard of care. StepUp is an open-label, multicentre, parallel group randomised controlled trial for women diagnosed with BV and their male partner. Current treatments directed solely to women result in unacceptably high rates of BV recurrence.
Bacterial vaginosis BV is an infection in the vagina. Males cannot develop bacterial vaginosis, but they can spread the infection. People with BV can get symptoms that include excess and discolored discharge from the vagina. It can cause a burning or itching sensation around the vagina, especially when urinating. Currently, doctors are unclear exactly how the infection starts.
Background: We determined the predictive accuracy of penile bacteria for incident BV in female sex partners. In this prospective cohort, we enrolled Kenyan men aged 18—35 and their female sex partners aged 16 and older. We assessed BV at baseline, 1, 6, and 12 months. Incident BV was defined as a Nugent score of 7—10 at a follow-up visit, following a Nugent score of 0—6 at baseline. Majority vote classifier combined the decisions of three machine learning classification algorithms Random Forest, Support Vector Machine, K Nearest Neighbor.